Состоявшиеся мероприятия

Clinical and biochemical data-driven drug re-purposing for anti-infective drugs

Дата проведения: 30.04.2020
Спикеры: Худошин Андрей Григорьевич
Организатор: Elsevier
Тип мероприятия: Вебинар
Drug repurposing has been shown to be advantageous for treating rare and common diseases. A data-driven drug repurposing approach may not only accelerate the time to reach the market but also helps in reducing costs and the clinical steps required, with the pre-existing knowledge of potential side-effects, special situations like age, gender or pregnancy, possibility to use combination with other drugs for more effective treatment, etc.

In the webinar, five data-driven strategies for antiviral and antibiotic drug research and development will be discussed:
• Search leveraging clinical data on drugs and biomolecules for treatment of related viral and bacterial disorders
• Search for substances reported to be active against related viruses and microbes in patents and articles
• Search for substances that interact with viral and bacterial proteins
• Investigation of compounds affecting human proteins, involved in the viral life cycle
• Assessment of the safety of drug candidate
Above approaches will be demonstrated, utilizing the clinical data from Embase and experimental biochemical data from Reaxys Medicinal Chemistry


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